Serie A Matchday 15 Top Betting Picks

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Napoli's forward Dries Mertens celebrates after scoring against Inter. Filippo Monteforte/AFP)

It’s a midweek round for Serie A and, unfortunately, there aren’t big clashes, which is unusual, but the scheduling makes it interesting anyway as many of the big teams are playing away, which raises the odds in spite of the likeliness of the expected results.

For example, Napoli at Sassuolo. So let’s dive into some Serie A odds for today.

Sassuolo vs. SSC Napoli

Wednesday, December 1, 2021 – 02:45 PM EST at Mapei Stadium

Napoli winning against Lazio during the Maradona celebration on Sunday night has been the best proof from the leader to demonstrate that they have digested the first defeat of the season at Inter, especially after suffering the injuries of Osimehn and Anguissa, who will likely be back in 2022.

It’s possible that the team got stronger as a reaction, so we must wait for a couple of more games to see if there really have not been any consequences, but certainly having a replacement as Mertens can help to switch from a system with a typical center-forward to a different one with a fake nine, especially if it’s the system that Napoli previously used for a long time.

Sassuolo was the surprise of the weekend after trashing 1-3 Milan, now former leaders and who were unbeaten at home, making them look hapless.

It was a big result to handle, for Sassuolo, a team that’s got a long tradition of being giant killers but that systematically have failed to maintain that mentality after a big result, always losing focus and never getting enough consistency.

Serie A Pick: Napoli to Win ML (-118) at Heritage Sports (visit our Heritage Sports Review)

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Bologna’s midfielder Andreas Skov Olsen goes for a header against Napoli. Filippo Monteforte/AFP)

Bologna FC vs. AS Roma

Wednesday, December 1, 2021 - 12:00 PM EST at Stadio Dall’Ara

Bologna is silently climbing the steps, holding steady the 9th place in the table, in a position they have been repeatedly before falling badly in the last stretch of games. Mihajlovic is making them more solid, counting on an attack that’s more consistent, remembering that not conceding any goal is the first goal you can score.

Roma has struggled in every one of their victories, nothing comes easy to them, and in every game, Mourinho has missed at least one player due to injury or covid. The latest is Pellegrini, whose injury will sideline him till 2022, and Felix, as the super youngster is ruled out due to covid.

For this reason, Mou might want to shut the door and wait for the moment Bologna will expose themselves, a mistake they often commit against defensive sides. But Roma must dose their efforts, as this weekend Inter will come.

Serie A Pick: Draw (+258) at YouWager (visit our YouWager Review)

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Inter Milan forward Lautaro Martinez (R) vies with Venezia midfielder Gianluca Busio. Andrea Pattaro/AFP)

Inter Milan vs. Spezia

Wednesday, December 1, 2021 - 12:00 PM EST at Stadio Giuseppe Meazza

The fixture in the weekend for Inter will be a special one, as it will be the first time ever that the old and loved Mourinho will face Inter as a rival. The manager of the treble will put end to an emotional week for the Nerazzurri, as Thiago Motta is the manager of Spezia.

The former center midfielder of Mourinho’s Inter is always proactive with his team, conceding spaces when attacking. Inter are learning to handle these games without troubles, but they ain’t there yet, and they always concede, at least, one concrete chance.

The odds on both teams to score + Over 3.5 goals are very valuable considering their record, so that’s the last Serie A pick for today.

Serie A Pick: Both Teams To Score + Over 3.5 Goals (+246) at BetOnline (visit our BetOnline Review)

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*The line and/or odds on picks in this article might have moved since the content was commissioned. For updated line movements, visit BMR’s free betting odds product.