Top Picks for NFL Week 10: Rams vs. 49ers

profile image of le.martin
Obo Okoronkwo #45, J.R. Reed #36, and Christian Rozeboom #56 of the Los Angeles Rams celebrate during an NFL preseason game. Dustin Bradford/Getty Images/AFP

NFL Week 10 does not have the greatest lines, in my opinion, but if you do your odds shopping at Bookmakers Review, you’ll be able to find good value. Read below for my NFL Prediction for the L.A. Rams vs. San Francisco 49ers. 

Los Angeles Rams vs. San Francisco 49ers

Monday, November 15, 2021 – 08:15 PM EDT at Levi’s Stadium

Los Angeles

The Rams are coming off of a 28-16 loss against the Titans in week 9. 

However, in their loss, Matt Stafford completed 31 out of 48 passes for 294 yards, 1 touchdown, and 2 interceptions. Meanwhile, Ryan Tannehil completed 19 out of 27 passes for 143 yards, 1 touchdown, and 1 interception in his victory. 

Overall, the Rams gained 4.7 yards per play with 347 total yards. They allowed 3.5 yards per play and 194 total yards against them. In this meeting, the Rams excelled on the pass with 253 yards; they only gained 94 yards on the ground. 

Their defense allowed 125 passing yards and 69 rushing yards. 

San Francisco

The 49ers are coming off of a 17-10 loss against the Cardinals in week 9. 

In their loss, Trey Lance led the pass with 15 completed catches out of 29 attempts for 192 yards and 1 interception. Meanwhile, Kyler Murray completed 22 out of 31 catches for 239 yards and 1 touchdown.

Overall, the 49ers gained 5.7 yards per play with 338 total yards. They allowed 5.1 yards per play and 304 total yards against them. San Francisco had a nice outing on the ground with 152 rushing yards; on the pass, they gained 186 yards. 

The Cardinals only had 94 rushing yards, but had a nice 210 yards on the pass. 


The current NFL Odds at your Top Sportsbooks are: L.A. Rams -4-110 and San Francisco 49ers +4-110 via BetOnline. 

Yes, both teams are coming off of losses, but we could all agree the Rams are the more efficient team in this matchup. 

In both of their losses, both the Rams and 49ers were able to gain yards down the field, just not finish a drive and score. 

Teams are bound to lose, but again, between the two, the Rams have been the more consistent team so far this season. They succeed on the pass with 308.4 total passing yards this season. The Rams are not perfect on the ground with an average of 103 rushing yards this season, however, the 49ers rushing attack has a lot of holes. They have only been able to put a stop to 131.6 rushing yards this season, and that just helps me see Cooper Kupp rushing all over them even more. 

The Rams should be able to put a halt to the 49ers overall and make it more difficult for them to finish a drive and score. 

This could be a trap play, but it’s very hard for me to back the 49ers in this one. San Francisco is 0-4 at home, while the Rams are 4-0 on the road. I’m backing the more consistent and trustworthy team in this one. 

NFL Pick: L.A. Rams -4 (-108) via BetOnline (Visit our BetOnline Review)

BetOnline logo
L.A. Rams -4 (-108)
Visit Site

*The line and/or odds on picks in this article might have moved since the content was commissioned. For updated line movements, visit BMR’s free betting odds product.