Week 6 of the NFL season kicks off Thursday night with a strange NFC matchup, as the defending Super Bowl champion Tampa Bay Buccaneers host the struggling Philadelphia Eagles. This comes on the heels of a profitable Week 5 where we nailed the majority of our NFL picks.
Sunday Night Football features a game that was a lot more attractive when it was announced. The aging Pittsburgh Steelers host the Russell Wilson-less Seattle Seahawks and are only 4.5-point favorites.
In between Thursday and Monday Night Football, there is a slew of other key matchups that will prove to be favorable for big plays. We’re targeting three games in particular to parlay. Let’s take a look at all the opening Week 6 NFL odds at BetOnline (visit our BetOnline Review).
Tampa Bay Buccaneers vs. Philadelphia Eagles
Thursday, October 14, 2021 – 08:20 PM EDT at Lincoln Financial Field
The Eagles, simply put, are one of the worst-coached offenses in the NFL right now. They managed just 273 total yards last week and have continued to forget to utilize Miles Sanders throughout the majority of the season. Nick Sirianni has tried to unleash Jalen Hurts and a fairly explosive cast of young receivers, but Hurts' impact falls well short of his raw numbers.
A team still scrambling to find their identity will not fare well on short notice against a team as hot as Tampa Bay. The Buccaneers are projected to have three 1,000 yard receivers and a tailback with more than 1,400 total yards. This team is as fierce as they come.
The Buccaneers simply need to be focused and motivated and they could push the over almost by themselves as they did in Week 5 against Miami.
NFL Pick: Over 51.5 (-110) with BetOnline
Cincinnati Bengals vs. Detroit Lions
Sunday, October 17, 2021 - 01:00 PM EDT at Ford Field
There's no question the Bengals have been frustrating to watch and bet on this year. Their offense has the potential to cover virtually any spread, and the defense has been shockingly effective despite a talent concern. And yet, they play conservatively and seem to forget their deep receiving corps.
They're an objectively decent team even with their flaws. Detroit is not, as they're unable to create any sort of downfield passing attack. Their game plan is predictably terrible and the lack of talent at receiver has left Jared Goff hanging in the wind.
I love that we're getting the Bengals +100 here. I expect the Bengals to win comfortably even if the Lions have done well to limit foes' scoring.
NFL Pick: Bengals -3.5 (+100) with BetOnline
NFL Pick: Under 48 (-110) with BetOnline
Dallas Cowboys vs. New England Patriots
Sunday, October 17, 2021 - 04:25 PM EDT at Gillette Stadium
Finally, Dallas is back and is quite good. Kellen Moore has mastered his usage of this deep array of playmakers, and Mike McCarthy isn't getting in the way of Moore's influence. This unit is good enough to win the NFC, and the defense is showing growth in 2021.
This line has grown by 3.5 points already and I would not allow it to swell anymore. New England has a great defense and will stifle this powerful unit. And Dallas' defense might provide enough holes for Mac Jones to suddenly find more of a stride, as they rank 31st in passing yards allowed. I think this ends up being a messy game where Dallas wins but far from a blowout.
NFL Pick: Cowboys -4.5 (-110) with BetOnline
NFL Pick: Under 50 (-110) with BetOnline
*The line and/or odds on picks in this article might have moved since the content was commissioned. For updated line movements, visit BMR’s free betting odds product.