Giants vs. Eagles NFL Week 16 Picks and Expert Insights

Jalen Hurts #1 of the Philadelphia Eagles. Mitchell Leff/Getty Images/AFP

Following an embarrassing home loss to the Dallas Cowboys in Week 15, the New York Giants (4-10) head not too far up the road to take on the Philadelphia Eagles.

The Eagles (7-7) will be coming off a short wee after taking down the Washington Football Team on Tuesday night.  Can the Giants squeak out another win before the season ends by sweeping the Eagles?

Below, we’ll take a look at the early NFL odds and best sportsbook to bet with. 

New York Giants vs. Philadelphia Eagles

Sunday, December 26, 2021 – 1:00 PM EST at Lincoln Financial Field

The Giants entered Week 15 as 10.5-point underdogs and are still the team getting the points for this matchup. As for the Eagles, they were 9-point favorites on Tuesday and remain the favorite in this game. According to BetOnline (visit our BetOnline Review), Philly is a 10-point favorite over New York with the over/under at 41.5.

The Matchup

Philadelphia has now won their last two games and covered, taking down Washington 27-17, along with blowing out the Jets the week before, 33-17. Starting QB Jalen Hurts returned from an ankle injury after missing Week 14  and scored, not one, but two QB sneaks and tossed one more while completing 20 of 25 passes for 296 yards.

His game wasn’t that perfect though, as he did throw one interception, his 9th on the season. Running back Miles Sanders also played a key role in the win by producing over 100 rushing yards. But Hurts and Sanders weren’t the only ones who performed well, as the defense put a stop to Washington’s run game.

The Eagles needed this win in order to stay in the playoff hunt and now have a 38% chance at a post-season birth now. The Giants Week 16 ending was a different story, losing to the Cowboys 21-6. Quarterback Mike Glennon threw for 99 yards with 3 interceptions as he led New York to their third straight loss.

However, the Giants did manage to beat the Eagles in Week 12 thanks to their defense. They picked off Hurts three times while holding him to just 129 yards. This game will be different this time after the Giants had to place their best wide receiver, Sterling Shepard, and starting quarterback, Daniel Jones, on the injured reserve.

And with the way Glennon is playing, the Giants could be turning to second-year quarterback Jake Fromm who made his first NFL debut vs. Dallas, completing 6 of 12 throws for 82 yards.


The Giants may have picked up a win over the Eagles in Week 12, but it’s obvious that their offense is a circus right now, especially at the quarterback position. The Eagles have their starting quarterback healthy and still have something to play for. If they can duplicate what they did on Tuesday, running the ball and stopping the run, then they should breeze by the Giants and cover.

NFL Pick: Philadelphia -10.5 (-105) with BetOnline (visit our BetOnline Review)

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Philadelphia -10.5 (-105)
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*The line and/or odds on picks in this article might have moved since the content was commissioned. For updated line movements, visit BMR’s free betting odds product.