Best Moneyline, ATS and Over/Under Bets for College Football Week 1

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Kedon Slovis #9 of the USC Trojans. Harry How/Getty Images/AFP

College football is finally here. After a soft opening in Week 0, we will see the best teams start their campaigns to compete for national championships. Alabama will try to hold off the competition, and the other teams will be trying to knock the crown off of Saban’s head.

There will be plenty of crucial games in the first week of the college football season. Alabama will play in a neutral site against D’Eriq King and the Miami Hurricanes. Clemson and Georgia will face off in a potential College Football Playoff preview. Penn State and Wisconsin will try to turn things around in their season opener against each other.

With so many questions heading into the season, it is hard to make predictions. Still, that can lead to solid payouts if you predict correctly. With that in mind, these are the best moneyline, ATS and over/under bets for the true start of the college football season. Whether it is because of value or accuracy, these are the moves to make.

USC Trojans vs. San Jose State Spartans

Saturday, Sept. 4, 2021 – 5:00 PM EDT at Los Angeles Memorial Coliseum

USC has some question marks, but the Trojans remain one of the best teams in the Pac-12. Kedon Slovis is ready to thrive with another year under center. Drake London is one of the best receivers in the conference, and USC has a stout defense and special teams. USC got lucky with some comebacks last year, and they won’t be nearly as lucky in 2021.

Still, they deserve more respect. They return 16 starters on offense and defense, and that includes their leader in passing yards, rushing yards and receiving yards. The depth is a bit of a question mark, but the top-level talent is there on both sides of the ball. With USC playing this game at home, it should not be close.

San Jose State is a quality team, but Nick Starkel won’t be enough to keep this one close. San Jose State gets a boost because they have a win under their belt already, but it was against Southern Utah. This game is USC’s, and they should win by at least three touchdowns. Anything less should result in Clay Helton’s seat getting even hotter.

NCAAF Pick: USC -14 (-115) with Bovada (visit our Bovada Review)

USC -14 (-115)
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Ole Miss Rebels vs. Louisville Cardinals

Monday, Sept. 6, 2021 - 8:00 PM EDT at Mercedes-Benz Stadium

This isn’t ideal value, but it is perfect for a parley. Ole Miss will begin their season at a neutral site against Louisville, and it would be shocking if they failed to win this game. Louisville went 4-7 last year, and the only reason they’ll do better this year is because of their easy conference schedule. They lack skill players., the offensive line is average at best and the defense will not be able to take a step forward with only six returning starters.

Ole Miss has an offensive mastermind as their head coach, and expectations for the Rebels are massive. Thanks to the return of Matt Corral, Ole Miss should have one of the best offenses in the SEC. Louisville lost five of their top seven tacklers from last year, and the new guys will be tasked with stopping a potent offense known for getting players open. That’s not a recipe for success, and Ole Miss will benefit because of it.

NCAAF Pick: Ole Miss (-300) with Bovada

Ole Miss (-300)
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Army Black Knights vs. Georgia State Panthers

Saturday, Sept. 4, 2021 -- 12:00 PM EDT at Center Parc Stadium

51.5 is an incredibly low total, but the under still makes sense for a very simple reason. Army loves to chew the clock, and that makes it easier to hit the under. Unders are common for Army due to their style of play. They only throw in obvious passing situations, and they rarely step out of bounds.

Most of the time on the clock is used in-between plays, leading to fewer drives and fewer scoring opportunities. Georgia State will try to push the tempo, but they can only do so much. If they have one or two turnovers, they could lose this game with only a few touchdowns being scored.

NCAAF Pick: Georgia State Under 51.5 (-108) with Heritage Sports (visit our Heritage Sports Review)

Georgia State Under 51.5 (-108)
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*The line and/or odds on picks in this article might have moved since the content was commissioned. For updated line movements, visit BMR’s free betting odds product.