Cubs vs. White Sox Free MLB Picks for May 28

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Johnny Cueto #47 of the Chicago White Sox pitches during the first inning of Game One of a doubleheader against the New York Yankees. Sarah Stier/Getty Images/AFP

The Chicago White Sox and Chicago Cubs will start a two-game mini-series over the weekend. The Windy City Rivalry is going to be exciting.

Which team will earn bragging rights in the first game of the series? Let’s see what the MLB odds tell us at the top sportsbooks!

Chicago Cubs vs. Chicago White Sox

Saturday, May 28, 2022- 07:15 PM EDT at Guaranteed Rate Field

Windy City Rivalry Game Preview

The Chicago Cubs and Chicago White Sox will start a new series on a Saturday. That doesn’t happen often in the MLB, but the two Chicago teams will begin a two-game weekend series against one another this weekend.

  • The White Sox had high expectations coming into the season but are currently just 22-22 on the season.
  • Meanwhile, the Cubs, who had no high expectations, are sitting at the bottom of the standings with an 18-26 record.

With both of these teams in different conferences and divisions, the only thing that matters is a win and bragging rights.

Which team can start off the mini-series with a bang? Here are our picks and predictions for the Chicago Cubs and Chicago White Sox game on Saturday, May 28.

Who Pitches For the Cubs Today?

It hasn’t been confirmed just yet, but it looks like Keegan Thompson will get the start for the Cubs. Thompson has a 4.96 xFIP in the last 30 days with 19.2% of strikeouts.

  • Against righties, Thompson has allowed a .345 wOBA and ISO of .267 in his last 34 plate appearances against them.
  • He’s keeping ground balls up and line drives down but the White Sox will have a lineup of more righties than lefties to help do some damage.

Who Pitches For the White Sox Today?

On the other hand, it’ll be Johnny Cueto who takes the mound for the White Sox.

  • Cueto has a 0.00 ERA to start the season with an xFIP of 3.88.
  • It’s small sample size for Cueto, as he’s pitched in two games, but overall, he’s looked really good through 12 innings.
  • Cueto is striking out 26.1% of batters and is limiting line drives while getting nearly 47% of ground balls.

Cubs Lineup Analysis

The Cubs have a .170 ISO and wOBA of .296 against righties in the last 30 days. However, the Cubs are also striking out 27.8% of the time using their projected lineup against righties in the last 30 days.

That should help Cueto keep things under control. There is a lot of power in the Cubs’ lineup but so far, Cueto has kept those power numbers down.

White Sox Lineup Analysis

The White Sox don’t have the better offense on paper but have the better matchup overall.

The White Sox will have at least five righties in the lineup against Thompson, who has struggled to get righties out more this season.

Cubs vs. White Sox: Game Prediction

Again, Thompson has struggled against righties in the last 30 days. The right-handed pitcher is only striking out 14.7% of righties in the last 30 days and he’s actually also walking 7.7% of lefties in the last 30 days.

There’s room for the White Sox to have some success, even though the team has struggled to find any kind of offense consistently this season.

The White Sox are only striking out 20.2% of the time in the last 30 days using their projected lineup against righties.

Thompson vs. Cueto Analysis

There’s reason to believe that the White Sox could put the ball in play against Thompson. A couple clutch hits would likely be enough with Cueto on the mound.

On the other hand, Johnny Cueto is bound to allow a run or two. But for now, we’ve got to run with him. He’s allowed no runs in two starts with 12 innings under his belt.

Cubs vs. Righties

The Cubs have a lot of power but also strike out a ton and have a low wOBA against righties in the last 30 days.

The Cubs have just two players hitting a high wOBA against righties. Cueto should be just fine tonight.

Cubs vs. White Sox: Who to Bet On?

Therefore, I’ll take the White Sox against the Cubs on the moneyline, at home. The White Sox should have the pieces to get a couple of runs against Thompson.

Meanwhile, the Cubs could end up striking out a whole lot against Cueto, giving them little opportunity to score runs.

The only way for the Cubs to win this game is to add a bunch of power. So far, Cueto has kept those power numbers down.

MLB Pick

With my MLB pick, let’s take the Chicago White Sox in this Chicago rivalry. This mini-series is going to be fun.

MLB Pick: White Sox (-145) with BetOnline (visit our BetOnline Review)

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*The line and/or odds on picks in this article might have moved since the content was commissioned. For updated line movements, visit BMR’s free betting odds product.