2025-26 NFL Offensive Player of the Year Odds & Picks
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Jason Lake
- November 19, 2025
We knew it would come to this. It only took a few games for the NFL Offensive Player of the Year odds to start taking shape; now that we’re well into the second half of the regular season, there’s no question we’re looking at a two-horse race – although there’s a clear leader on the NFL player futures market at Bookmakers Review as we go to press.
2025-26 NFL Offensive Player of the Year Players to Watch
The nature of this award made our two horses the obvious Offensive Player of the Year candidates even before we reached October.
Recent years have seen the NFL’s Most Valuable Player Award handed out to quarterbacks, leaving the OPOY as a consolation prize for running backs and wide receivers; the Associated Press has yet to give this award to a tight end. And they probably won’t this year, judging by the NFL OPOY odds heading into Week 12.
| Position | Player Name | Team | Odds |
|---|---|---|---|
| 1 | Jonathan Taylor | Colts | -425 |
| 2 | Jaxon Smith-Njigba | Seahawks | +290 |
| 3 | Malik Nabers | Giants | +2500 |
| 4 | Christian McCaffrey | 49ers | +3000 |
Indianapolis Colts’ Jonathan Taylor (-425)
Maybe Tom Vek was right: This is a one-horse race. Jonathan Taylor finished a distant second to Los Angeles Rams WR Cooper Kupp in the 2021 OPOY vote, despite leading the league in yards from scrimmage and total touchdowns – but Taylor is performing at an even higher level this year, and Kupp (now with Seattle) hasn’t even been to the Pro Bowl since that magical 2021 campaign.
The other big difference for Taylor is his quarterback. Four years ago, the Colts were squeezing one good year out of former MVP candidate Carson Wentz (60.6 QBR); this time, it’s Daniel Jones (66.6 QBR) under center, and while Jones has outperformed Wentz thus far, there’s been some turbulence along the way, enough to remind Indianapolis fans of how shaky things got for Jones when he was with the New York Giants. Taylor is the bell cow that Jones can lean on for support. It’s an easy narrative for the OPOY voters to get behind.
Seattle Seahawks’ Jaxon Smith-Njigba (+250)
It’s also the same narrative driving the last real threat to Taylor’s ascension. Jaxon Smith-Njigba is the No. 1 wideout for the Seahawks, who have a reclamation project of their own in QB Sam Darnold. As with Jones, things have gone mostly well for Darnold (71.3 QBR), but not always – see his Week 11 performance against the Rams, where he threw four interceptions and zero TD passes.
While Darnold may have his warts, the Seahawks offense has been electric in its first year under offensive coordinator Klint Kubiak, who got promising results last year from the New Orleans Saints before QB Derek Carr and others got hurt. Smith-Njigba leads the league at press time with 1,146 receiving yards on 11.8 yards per target; he might find yet another level now that Seattle has added former Saints WR Rashid Shaheed, but that dreaded East Coast Bias might be all it takes to keep JSN from overtaking Taylor.
Betting On The Favorites and What To Do Next
If you’re willing to eat some chalk, Taylor is the easy choice on the NFL Offensive Player of the Year odds board – the only thing that might stop him at this point is health. But Taylor’s OPOY odds will only get shorter as we get closer to the end of the regular season, so get those bets in now, and sign up for multiple sportsbooks so you can get the best price available for your wager.
Shop Smart With Bookmakers Review
Speaking of best prices, the OPOY odds you see above were from Bovada, and they had one of the highest payouts available for Smith-Njigba if you’re thinking of betting on the dark horse. Our comprehensive Bovada review will help you decide whether you should open a betting account there and take advantage.
Shopping for lines is half the battle when you bet on football, so keep it locked in here at Bookmakers Review for live NFL odds across all the major offshore sportsbooks, and may the prolate spheroid be with you.
*The line and/or odds on picks in this article might have moved since the content was commissioned. For updated line movements, visit BMR’s free betting odds product.
