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2025-26 College Football Heisman Odds & Picks

Michigan State v Indiana
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Much has changed since the beginning of the season, and so too have the NCAAF Heisman Trophy odds. Earlier this season, Oklahoma quarterback John Mateer and Texas gunslinger Arch Manning were two preseason favorites, but both have dropped out of the Heisman Trophy picture.

The current NCAAF Heisman Trophy odds feature an entirely new batch of favorites, and now that the season is more than midway through, let’s analyze the candidates and find out who the oddsmakers’ favorites are entering the homestretch of the season.

2025 NCAAF Heisman Trophy Players to Watch

The NCAAF Heisman Trophy betting odds as of Week 11 show the top 10 hopefuls to win college football’s most coveted personal award. It is not all that surprising that the defending national champions and the No. 1-ranked team in the nation would have their quarterback at the head of the class in the form of sophomore Julian Sayin.

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NCAAF Championship Winner Odds

PlayerTeamOdds
Julian SayinOhio State+175
Fernando MendozaIndiana+225
Ty SimpsonAlabama+310
Marcel ReedTexas A&M+700
Gunner StocktonGeorgia+1800
Devon DampierUtah+2200
Sam LeavittArizona State+2500
Behren MortonTexas Tech+3300
Diego PaviaVanderbilt+3300
Drew AllarPenn State+3300

Quarterbacks

Fernando Mendoza (Indiana +225)

Speaking of surprises, who would have thought that a school renowned for its basketball program would be the talk of the college football world? The Indiana Hoosiers are undefeated and perched at the top of the Big Ten, alongside Ohio State.

And although Indiana has executed impressively on both sides of the ball, the quarterback is entitled to his verbal bouquets, and the recipient of those flowers is U Cal transfer Fernando Mendoza. At 6’5” tall, Mendoza has the physical attributes that make the pro scouts salivate.

After nine games at the helm of this year’s Cinderella story, Mendoza has tossed for 25 touchdowns (along with four rushing TDs) for over 2100 yards against just five interceptions and is completing over 72% of his passes on a team that has gone above and beyond all expectations.

Indiana has just three games left on their regular-season slate. All their opponents are unranked, including the disappointing Penn State, Wisconsin, and Purdue. Should Mendoza continue to perform at this elite level, he could be a steal at +225 to take home the hardware.

Fernando Mendoza To Win Heisman Trophy (+225)
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Ty Simpson (Alabama +310)

The college portal has made it fashionable to transfer out of a program if the moon and the stars don’t align into a starting position that manifests in oodles of NIL money and a ticket to the pros. But Ty Simpson was having none of it. He was a Saban recruit as far back as 2022, and although he never got the starting nod under the legendary coach, he redshirted and stayed the course in Tuscaloosa.

Whether you love or loathe Alabama, you can’t help but respect Simpson’s devout loyalty to the program. His patience was rewarded this season when he was named the starting quarterback, and he has validated that choice with an outstanding performance this season.

The 6’2” redshirt junior has been surgically precise this season, tossing for 2,184 yards with 20 passing touchdowns and only one pick. He also has a pair of TD scampers on his resume this season, but Simpson has been the glue that has held this Bama squad together, even after they shockingly lost their opener to Florida State as 13-point road chalk.

The Crimson Tide is 7-1 with four dates remaining on their regular season schedule, including dates with LSU, No. 11 Oklahoma, Eastern Illinois, and a finale against ancient SEC rival Auburn. Will Simpson win the Heisman? Probably not, as Sayin and Mendoza will likely end with undefeated records, but at +310, there are worse future bets you could make.

Ty Simpson To Win Heisman Trophy (+310)
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Don’t Let the Odds Pass You By

If you are interested in betting on the Heisman Trophy, make sure to take advantage of the many tools available at Bookmakers Review. Review the teams’ opening schedule and find out if the offenses have a chance to get to know each other, courtesy of the weak defenses they may face in the early going. Building confidence early is a major advantage, and we will likely see this chemistry come about early and continue to improve.

The NCAAF Heisman Trophy odds are dynamic and move with the money being wagered on the candidates. Therefore, if you see an opportunity, pounce on it, and make sure to have funded accounts in at least two or more of the best online sportsbooks shown right here at Bookmakers Review.

More Picks from Our Experts

Don’t miss Donnie RightSide’s expert breakdown for winning the Heisman Trophy, and for more top NCAAF picks, check out our YouTube channel for daily betting insights!


*The line and/or odds on picks in this article might have moved since the content was commissioned. For updated line movements, visit BMR’s free betting odds product.

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